For the third year in a row, Aprilia will race in a special (RED) livery in support of the AIDS charity during this weekend's Valencia MotoGP finale.
The event will also mark the final grand prix for Scott Redding, who is switching to the British Superbike championship with PBM Ducati for 2019.
"Valencia will be my last MotoGP race after 10 years," said Redding, who took the first of his four grand prix victories during a debut 2008 season in 125cc and was later Moto2 title runner-up before joining the premier-class in 2014, where he has taken two podiums.
"It will certainly be an emotional experience to close an important chapter of my career and I will try to do it in the best possible way.
"During these years, the fans have been exceptional and that has meant a lot to me. I hope they will continue to follow me with the same warmth."
The colourful Englishman is 21st in the world championship, scoring points once since the summer break.
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Team-mate Aleix Espargaro, who will remain at Aprilia alongside new signing Andrea Iannone for 2019, is also looking for a strong end to an often-difficult season.
"In recent races we have shown encouraging signs and I want to finish out the championship in the best possible way," said the Spaniard, who sits 15th in the world championship, with the clear highlight of matching Aprilia's best four-stroke result with sixth at Aragon.
"It was certainly not an easy season, but we never stopped working and the final race is always a special opportunity because from Sunday on, we will officially begin our 2019 season with the first tests.
"We will also be racing in the (RED) livery. This is an important initiative and I am honoured to be able to provide my contribution to it."
